The conservation of great apes faces many challenges, one of which is the threat of infectious disease outbreaks. Zoonotic transmission of respiratory diseases from humans to wild great apes has recently been confirmed. Since respiratory disease is one of the major causes of death in both gorillas and chimpanzees, this gives reason for major concern. Little is known about the risks of Disease transmission from humans to great apes in natural environments, and there is a need for systematic risk evaluation. Researchers, conservation staff and tourists spend time in very close proximity of wild great apes, sometimes during long time periods, which poses a potential risk of disease spillover. However, the presence of researchers and tourists has been shown to decrease the risk of poaching, making the matter increasingly complex.

Emerging infectious diseases are a recurring threat to both human and animal health. Understanding the multiple causes behind the emergence of new diseases is key to the prevention of new and potentially devastating outbreaks. The list of underlying causes is long, including a variety of anthropogenic, environmental, molecular and climatic changes that promote the emergence and spread of disease. Two of these factors are central to the emergence of new diseases and receive special attention in this study. The spread of disease from wildlife to livestock and diseases that spread from animals to humans (zoonoses) are of importance as they implicated in the majority of EID events.

Bacillus anthracis is the causative agent of anthrax, a serious and globally distributed zoonosis affecting a wide range of wild and domestic animals, invariably also humans. However, although known to humans since biblical times, much remains to be elucidated concerning the ecology and transmission of this bacterium. Of particular interest is the Bacillus anthracis spore, the uptake of which is the predominant way to contract anthrax and which is legendary for its resilience in the environment and thus crucial for persistence and spread of the disease. Hence, the aim of this study is to review the natural transmission of Bacillus anthracis and investigate potential means by which soil persisting Bacillus anthracis spores reach concentrations sufficient to infect susceptible hosts. When reviewing the literature, three different theories can be distinguished. Firstly, ?the incubator area? hypothesis suggests that favourable soil factors, possibly in association with amoebas, may constitute an environment supporting repeated spore-bacterium-spore cycling, thus increasing the local amount of spores.

Although known and feared for thousands of years, rabies remains a real and present threat to thousands of people, especially in low- and middle income countries. In India, rabies is an endemic disease, causing human deaths every year. The primary mode of transmission is through the bite of an infected dog. Fighting the disease in the dog population through vaccinations remains the most efficient way to eradicate the disease. The knowledge of rabies in India is unsatisfactory, as a lot of people lack awareness about the severity of the disease and the importance of washing the bitten area and seeking medical attention for post exposure prophylaxis when bitten by a dog.

Bull terrier hereditary nephritis is caused by a mutation that leads to an inadequate synthesis of collagen type IV, which is an important component in the basement membranes. The inheritance of the mutation is autosomal dominant in bull terriers and progression to renal failure takes variable time, from several months to ten years. Proteinuria is the first clinical sign of the disease and the diagnosis is confirmed by transmission electron microscopy of renal tissue where typical ultrastructural changes in the glomerular basement membrane (GBM), thickening and multilaminar splitting are found. This study was performed in order to find out the occurrence of hereditary nephritis in bull terriers in Sweden through examination of urine samples and renal tissue and comparisons with how the disease is described in the literature. Urine samples from 76 Swedish bull terriers were collected and examined for proteinuria.

Africa is expected to go through a rapid urbanization over the next four decades and the demand for food is increasing in the rapidly growing urban and peri-urban (UPU) areas. Keeping livestock in urban areas is in particular associated with health hazards. This is due to close interaction between humans and animals, and it has been shown that zoonotic diseases are increasing in urban areas. The benefits of urban and peri-urban agriculture (UPA) are related to improved food security, in particular among low-income groups. Apart from the negative public health impact of zoonotic diseases, animal disease could have a devastating impact on the economy and food security of many households in these areas. In the present study, three important endemic diseases, including brucellosis, salmonellosis and Bovine viral diarrhea (BVD), were analyzed in regard to seroprevalence and risk factors.

Emerging infectious diseases poses a great future threat, not only to humans but also to domestic animals and wildlife. Even though the majority of these infections only cause minor health problems, the relatively recent emergence of HIV clearly illustrates that the next major human pandemic may surface at any time. Regardless of what the name indicates, most emerging human pathogens are not believed to be recently evolved, but to have existed previously in the natural environment. Most emerging pathogens are zoonotic, i.e. able to infect animals besides humans.

Francisella tularensis, the causative agent of the zoonotic disease tularaemia, is highly contagious and potentially fatal for a wide range of wildlife species of the northern hemisphere, also humans. Although recognized as a pathogen for over 100 years, much still remains to be elucidated concerning the ecology and transmission of the bacterium, hence this literature overview aims at compiling data regarding the aquatic association and the role of mosquitoes in transmission of Francisella tularensis subspecies holartica, the sole subspecies in Sweden. While a linkage between the bacterium and natural waters stands beyond dispute, there is no consensus in the literature concerning its potential as a reservoir. However, two prevailing theories can be distinguished; one proposes the water association being mammaldependent and thus merely the result of contamination from semi-aquatic mammals living in close vicinity to the water source. The other, quite contrary, suggests mammal-independence and hence that water, possibly in association with protozoa, serves as an environmental reservoir for the bacterium.

Parkinson's disease is a progressive degenerative neurological disorder. In Sweden there are 15 000-20 000 individuals affected by the disease.The aim of this study was to investigate the prevalence of oral diseases in individuals with Parkinson's disease. The material for the literature review was gathered in the medical database PubMed. Keywords used for the data research were ?Parkinson?s disease?, ?oral diseases?, ?dry mouth?, ?gingivitis?, ?caries? and ?periodontitis?.

Background:Alzheimer's disease is a disease that primarily affects the elderly but also younger people. Alzheimer's disease is a type of dementia which means that you get changes in the cerebral cortex and cells gradually die. The disease causes memory loss and things that were obvious before will be difficult for the sufferer. Alzheimer's disease also affects next of kin to a large degree; they will have to take a great responsibility. The next of kin are entitled to support from healthcare.Aim:The aim was to highlight next of kin' experiences of healthcare to their family members with Alzheimer's disease.Method: The study was based on narratives, which in this case means analysis of autobiographies.

The aim of the study was to describe how women and men with diagnosed heart disease experience their health-related quality of life and what differences there is between genders in their quality of life and also describe problems after receiving the diagnosis. The study also aimed to describe rehabilitation of patients with heart disease. The study was a descriptive literature study based on scientific articles. It emerged that both women and men with heart disease experienced lower quality of life compared to normative data. There was a significant difference between women and men both one year and three years after receiving the diagnosis heart disease, which showed that women experienced lower quality of life than men.

This report is introduced with a presentation of fundamental electromagnetic theories, which have helped a lot in the achievement of methods for calculation and design of microstrip transmission lines and circulators. The used software for the work is also based on these theories. General considerations when designing microstrip solutions, such as different types of transmission lines and circulators, are then presented. Especially the design steps for microstrip lines, which have been used in this project, are described. Discontinuities, like bends of microstrip lines, are treated and simulated.

Background: Inflammatory bowel disease (IBD) is an umbrella term for ulcerative colitis and Crohn's disease. These are characterized by a chronic inflammation of the intestinal mucosa. Living with chronic illness meant that life changed significantly. Quality of life was affected for these individuals and was stressful in their lives. Aim: The aim was to describe the experiences of living with inflammatory bowel disease. Method: A qualitative literature review was chosen to analyze articles that were related to the aim of this study. Results: Based on the chosen articles five themes were created; Commuting between hope and fear, symptoms of the disease and medication become everyday focus, struggling with  the new identity, desire to control the disease- do I control my illness or does it control me and social relationships are affected. Conclusion: Inflammatory bowel disease is a distressing disease and can cause limitations in social life due to lack of knowledge by others about the disease. The affected felt a loss of control in their life due to the difficulty in managing the symptoms.

This thesis has the overall objective to develop the optimum sealing system between the retarder and transmission. Today, there is a pressure-relief and two radial seals separation between the retarder and transmission. It has been found that carbon residue formation may occur between retarder axle and seal lips with, in some cases, leakage as a result.We have in this thesis tried to explain the phenomenon of carbon residue, how it is formed and why it can be seen just on the seals? A rig test was conducted where we show how friction, speed, transmission temperature and mitigation phases of the retarder affects temperatures in the sealing environment. Factors affecting the coke structure are reported, together with proposals for measures that provide a mitigating seal environment.

Background:Alzheimer's disease is a disease that primarily affects the elderly but also younger people. Alzheimer's disease is a type of dementia which means that you get changes in the cerebral cortex and cells gradually die. The disease causes memory loss and things that were obvious before will be difficult for the sufferer. Alzheimer's disease also affects next of kin to a large degree; they will have to take a great responsibility. The next of kin are entitled to support from healthcare.Aim:The aim was to highlight next of kin' experiences of healthcare to their family members with Alzheimer's disease.Method: The study was based on narratives, which in this case means analysis of autobiographies.